Granny Storm Crow's List - January 2015
FOR THE CURRENT LIST PLEASE GO TO www.grannystormcrowslist.wordpress.com
“We have preliminary data showing that for certain medical conditions and symptoms that marijuana can be helpful, so I think we have to use that data to drive policy making”. Those are the words of the US Surgeon General, Dr. Vivek Murthy. Not 'may be helpful', CAN be helpful! Our nation’s top doctor has quite publicly recognized that cannabis does have real medical uses! The age of 'no recognized medical use' has passed! Our laws 'merely' need to catch up with this 'new medical reality'! (Are you registered to vote?)
There have been several exciting studies published recently, but one that really stands out is “Effect of Marijuana Use on Outcomes in Traumatic Brain Injury”. It’s a very small study, fewer than 500 people, but the results are so dramatic that it is very hard to ignore them! Apparently even recreational use of cannabis may greatly increase the odds of surviving a brain trauma! In a nutshell, the mortality rate for non-users was 11.5%, while cannabis users had a rate of 2.4%! But it’s a small study and they need to repeat it with larger numbers! Yet, since it is a statistical study based on data that is normally collected in trauma cases, namely, drug testing and mortality rates in head trauma, it should be simple to duplicate this study to confirm it! A second important study is “Daily Marijuana Use Is Not Associated With Brain Morphometric Measures In Adolescents Or Adults” which shows that after taking into account certain factors overlooked by previous studies (alcohol use, age, gender, etc.,) there is no 'brain shrinkage'. And the remarkable safety of cannabis was once again confirmed in "Comparative Risk Assessment of Alcohol, Tobacco, Cannabis and Other Illicit Drugs Using the Margin of Exposure Approach". Of all the drugs that they compared, only cannabis was considered 'low risk'.
Studies are coming out at such a rate that I have created a new section for the 2000 to 2009 studies. The List now contains only the most recent studies, those from 2010 to 2015 and the '2000 to 2009' studies. The 'old Pre-2000 studies' and the Mini-Dictionary are located here. Although these studies are older, there is a lot of good information here! The large 'Endocannabinoid System 2010 – 2015' category begins the third section, followed by the much smaller 'Endocannabinoid Genetics'. Next comes the 'Phytocannabinoids' which has blossomed into a category in its own right, and finally, the 'Synthetic Cannabinoids and Compounds That Affect the Endocannabinoid System'.
Share the List! Our government has lied to us for decades about this healing herb. It is time for the truth! There is so much more to cannabis than just the 'high'! Once the medical facts become known, the need for full legalization becomes obvious! And as my grandfather once said, “If the truth won’t do, then something is wrong!”
Goodness! How my List has grown over the last few months! And there
have been some
rather unexpected new “branchings” in the List recently.
Acetaminophen, black tea, flax, echinacea, and magnolias? How did
they manage to sneak into my list on Cannabis, Cannabinoids
and the Endocannabinoid System?
The answer is simple. These plants all contain compounds that interact with receptors in the Endocannabinoid System. Science has discovered that Cannabinoids are, indeed, made by other plants. So far, none of them cause the same dramatic psychoactive CB1 receptor reaction (the high) as THC. They seem to be mostly limited to the CB2 receptors (no high, just healing).
Acetaminophen, on the other hand, is transformed by your body into a compound called AM-404, which blocks the break-down of anandamide, your body’s own version of THC. Just like THC, anandamide makes you “feel good” and decreases pain. Blocking the break-down of the fragile anandamide by AM-404 results in more anandamide being in your body, relieving your pain. The acetaminophen, itself, does nothing to relieve your pain!
As much as I would like it to be, Cannabis is not 100% safe - nothing is! There is something you need to understand about the Endocannabinoid System - it is a system of checks and balances. The amounts of Endocannabinoids vary according to the body’s needs. As an example, during a woman’s ovulation, her anandamide levels spike, then drop drastically for the implantation of the egg. THC during ovulation would have little effect, but just days later, THC might interfere with implantation. Women trying to get pregnant should avoid Cannabis.
Teens under the age of 16 should not be using Cannabis unless there is a medical reason. The adolescent brain undergoes a “rewiring job” and the Endocannabinoid System is right in the middle of things. The fear is that THC will cause “misconnections” resulting in subtle personality changes or neurosis. Like alcohol, Cannabis should normally be reserved for adults.
Likewise, cancer is not just one disease, which is why one treatment does not work on all types of cancer. Most cancers appear to be slowed by THC, but there are a few rare exceptions. When exposed to THC or similar synthetics, A549 lung cancer cells start reproducing, while exposure to CBD slows them down*. The usual “high THC” RSO could be a disaster for a small minority of cancer patients. We need more research, but that can’t happen without legalization!
Our government has lied to us about the effects of Cannabis for over seven decades. They have blocked virtually all research into Cannabis and how it heals. They have ranked a never fatal herbal medicine with the most deadly kinds of drugs, against all scientific evidence! Yet, somehow, that inconvenient truth keeps coming out - Cannabis heals! It is time that we, as a nation, demand that the truth be openly acknowledged and research into this amazing plant begun! As my Grandfather said, “If the truth won’t do, then something is wrong”!
And as an afterthought, a few suggestions for dealing with the List and a request -
Find a free “PDF to WORD” program and change the List to a WORD document. Then click the “Find” function and a very helpful navigation index should pop up. Just click the cursor on the section you want and you go there. Having the List in WORD enables you to modify it to suit your needs, new studies, rearrange things, or add comments, etc. I have no problem with this as long as it is for your home copy only.
Try reading the news articles first, then move on to the studies.
Print up a copy of the Mini-dictionary to have handy while reading the studies.
When reading studies, always have a second window open to plug in those “weird words”. Usually you won’t even need to open a link - the definition is often visible in the excerpts that are shown. Write down the definition on a 3 x 5 card, or go to your Mini-dictionary add it there.
As studies age, they are often freed up for public use. I will often find a new abstract at PubMed (“ncbi” in the URL), but during the time between my collecting the abstract, and your clicking the link, they sometimes will make the study “open access”. My link will take you to just the abstract, but up in the right corner will sometimes be a link to the free full study either at PubMed, or another site. Always check for the full study! Also, don’t be afraid of going to PubMed - they don’t bite, and the site is free, simple and user-friendly.
Older studies often have the basic information on Cannabis that many people will find helpful, and they are usually easier to read! Don’t pass them up just because they are not the latest!
Remember that studying the Endocannabinoid System (ECS) is brand-new science. There are bound to be contradicting studies, and studies with mixed results! Scientists or “just regular folks”, all of us are figuring out and learning about the ECS as we go along!
I encourage you to forward the List to your friends. Knowledge unshared, is knowledge wasted! I’ve given my List to you for free and hope you will share it freely in return.
My List is always available by emailing [email protected]
You are most welcome to post up the List (or its complete sections), unmodified, at your blog, or website or forum. If you want to “pretty it up”, please contact me first.
Please do NOT post up or share a modified copy of my List! The List is “my baby” and I wish to keep it that way! I’m the one who has spent 1000s of hours creating this database, and I feel that there should only be my versions (or ones I have approved) of the List available online.
And one last note - I want to thank “Deb T.” and “Anne M.” for all the help they have given me over the years dealing with this “monster” of mine! Hugs to you both!
*Critical appraisal of the potential use of cannabinoids in cancer management. (link to PDF – 2013) http://www.dovepress.com/critical-appraisal-of-the-potential-use-of-cannabinoids-in-cancer-mana-a14216